IndraLab

Statements


| 3

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"Piceatannol, a metabolite of resveratrol, attenuates atopic dermatitis by targeting Janus kinase 1."

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"Piceatannol also inhibits JAK-1, which is a key member of the STAT pathway that is crucial in controlling cellular activities in response to extracellular cytokines and is a COX-2-inducible enzyme involved in inflammation and carcinogenesis."

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"In contrast, additional treatment with Piceatannol which inhibit the NF-kappaB and JAK-1 and STAT signaling [XREF_BIBR] abolished the effect of betulin to increase IL-12p70."