IndraLab

Statements

OTUD7B binds POLR2A. 4 / 4
| 2 2
sparser
"CO-IP assay in Hek 293T cells, IP with anti-Cezanne, validated the binding of Cezanne and POLR2A (Fig. xref )."
37596251
reach
"However, the public CHIP data from the Cistrome project (http://cistrome.org/) showed that POLR2A, rather than CTCF, binds the transcription start site of PIK3C2A (Fig. 5K) and we chose POLR2A as the candidate TF.CO-IP assay in Hek 293T cells, IP with anti-Cezanne, validated the binding of Cezanne and POLR2A (Fig. 5L)."
37596251
reach
"Indeed, Cezanne could bind and stabilize POLR2A and deubiquitinate the K48-linked ubiquitination of POLR2A (Fig. 5L–N)."
37596251
sparser
"In this study, with the help of a public database and LC-MS/MS analysis, we identified a transcription factor, called POLR2A, which might be the mediator between Cezanne and PIK3C2A. Indeed, Cezanne could bind and stabilize POLR2A and deubiquitinate the K48-linked ubiquitination of POLR2A (Fig. xref )."
37596251