IndraLab

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USP54 activates PLK4. 1 / 1
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reach
"These results suggested that USP54 plays a key role in the CEP120-mediated stabilization of PLK4 and is expected to become a novel target for the treatment of GC.In conclusion, we revealed the key role of the CEP120-USP54-PLK4 axis in centrosome amplification and GC progression."