IndraLab

Statements


KCNH2 activates TNF. 1 / 1
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reach
"In hERG positive SKBr3, SH-SY5Y, and HL-1 cells, apoptosis occurs via a caspase 3 dependent pathway in response to extracellular administration of H 2 O 2 or TNFalpha (tumor necrosis factor alpha), whereas selective inhibition of hERG conductance by dofetilide attenuates the proapoptotic effect of H 2 O 2 and TNFalpha."