IndraLab

Statements

USP22 inhibits cisplatin. 10 / 10
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"USP22 inhibition restores cisplatin sensitivity in cisplatin-resistant lung cancer cells.Cisplatin can induce cell death by activating mitochondrial apoptosis."
35935969
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"The Cisplatin Sensitivity in Cisplatin Resistant A549 and CDDP Cells Was Restored by USP22 Inhibition."
28567015
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"These results indicate that the cisplatin sensitivity in cisplatin resistant A549 and CDDP cells was restored by USP22 inhibition."
28567015
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"In addition, the cisplatin sensitivity in cisplatin resistant A549 and CDDP cells was restored by USP22 inhibition in vivo and vitro."
28567015
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"USP22 directly interacts with PALB2 to promote DNA homologous recombination repair and inhibit the killing effect of cisplatin on cancer cells."
35935969
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"The cisplatin sensitivity in cisplatin resistant A549 and CDDP cells was restored by USP22 inhibition in vivo and vitro."
28567015
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"Silencing USP22 can inhibit the Wnt/β-catenin pathway to reduce cell stemness and enhance the sensitivity of PC cells to cisplatin."
35623308
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"Inhibiting USP22 Expression Enhanced Cisplatin Sensitivity in Cisplatin Resistant A549 and CDDP Cell Nude Mouse Xenografts."
28567015
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"These results suggest that inhibiting USP22 expression enhanced cisplatin sensitivity in lung adenocarcinoma by downregulation of Sirt1 and gammaH2AX in vivo."
28567015
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"Furthermore, USP22 knockout significantly impaired non homologous DNA damage repair capacity, enhanced cisplatin and irradiation induced apoptosis in these cells."
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