IndraLab

Statements



reach
"The Ca 2+ -activated K + channel (MaxiK) forms a complex with the GABA transporter 3 (GAT3; Slc6a11) ( Singh et al., 2016 ), while another K + channel (KCNA2/Kv1.2) interacts with LAT1 ( Baronas et al[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"The structure of the Ca bound human BK channel in complex with the β4 subunit with PDB code: 6V22 (21) was used for protein–peptide docking."

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"Such a lack of size specificity is in striking contrast to the dissociation constants of Mg 2+ and Ca 2+ binding to the high-affinity Ca 2+ binding site of mSlo1 at the open state, which are 4.73–5.6 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"However, CO can still drive channel opening by binding to heme once bound to Slo1 BK Ca 59."

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"The cytosolic region of Slo1 binds to calcium via the calcium bowl located at the distal end of its hydrophilic tail; therefore, these channels are sensitive to changes in both membrane potential and [Ca 2+]."