IndraLab

Statements

Nelfinavir inhibits KCNH2. 2 / 2
| 2
reach
"In vitro, lopinavir, nelfinavir, ritonavir, and saquinavir caused dose dependent hERG channel blockade."
33345848
reach
"Drug induced QT prolongation is usually caused by block of human ether-a-go-go-related gene (HERG) potassium channels, and we showed that lopinavir, nelfinavir, ritonavir, and saquinavir caused dose dependent block of HERG channels heterologously expressed in HEK293 cells in vitro."
15721475