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Magnesium oxide inhibits RELA. 2 / 2

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"The EA.hy926 cells were then treated with cycloheximide (CHX) and MGO, as indicated in Figure XREF_FIG C, and the degradation of the p65 protein was facilitated by MGO treatment, indicating that MGO reduces the stability of the p65 protein."

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"In line with our assumption, a recent report convincingly showed that MGO inhibited NF-κB activation by targeting Cys 38 of the p65 subunit [29] ."

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Magnesium oxide inhibits RELA. 2 / 2

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