IndraLab

Statements

USP22 activates CRPC. 3 / 3
| 3
reach
"USP22 promotes CRPC through enhanced ligand independent and androgen stimulated AR transcriptional activity and sustained AR activity in the presence of antagonists, concomitant with AR protein accumulation."
24197134
reach
"In prostate cancer, USP22 predicts disease outcome and promotes the CRPC phenotype by controlling AR and MYC dual regulation (63)."
35935969
reach
"Given the ability of USP22 to enhance AR accumulation, AR activity, and CRPC, the biological impact of a model of tetracycline inducible shUSP22 was developed in therapy sensitive PCa cells."
24197134