IndraLab

Statements

USP4 activates RIGI. 5 / 5
| 5
reach
"In contrast, USP4 and USP15 enhance the stability of RIG-I by reducing K48-linked ubiquitylation."
40126553
reach
"On the other hand, USP4 and USP15 enhance the stability of RIG-I and TRIM25, respectively, by proteolytically cleaving K48 linked ubiquitylation from these molecules XREF_BIBR, XREF_BIBR."
31792373
reach
"In contrast, USP4 and USP15 enhance the stability of RIG-I by hydrolyzing the K48-linked ubiquitin chain and exerting a positive regulatory effect ."
37945923
reach
"Ubiquitin-specific protease (USP4), a key modulator of RLR signaling pathway, increases the stability of RIG-I protein through deubiquitination and further promotes the production of IFN-I (57)."
36532076
reach
"Deubiquitinase USP4 and USP15 can increase the stability of RIG-I and TRIM25 by decreasing their K48-linked ubiquitination (Wang et al., 2013; Pauli et al., 2014)."
40126553