IndraLab

Statements


EIF3F inhibits ERK. 2 / 2
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"Furthermore, eIF3f can suppress Akt and ERK signaling, as well as stabilize p53 [60] In our data, eIF3f was also down-regulated, as is the case in melanoma and pancreatic cancer."

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"EIF3f overexpression activates p53 and Bax and inhibits Akt and ERK signaling."