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USP8 decreases the amount of BAX. 3 / 3
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"The results of western blot indicated that knockdown of USP8 down-regulated the expression of Cyclin D1, CDK4, CDK6, p-AKT, and Bcl2, and up-regulated the expression of Bax."
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"Western blot results revealed that USP8 knockdown significantly promoted the protein expression of Bax, cleaved caspase-3, and cleaved PARP and markedly suppressed the protein expression of Bcl-2 in J[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In addition, USP8 significantly inhibited the expression of Bax protein and promoted the increased Bcl-2 protein levels ( Fig. 2 F)."
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