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SP1 activates KCNH2. 1 / 1
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"It has been reported that the transcription factor Sp1 modulates the activities of the KCNQ1 (which encodes KvLQT1) and KCNH2 (which encodes HERG1) promoters, suggesting that the differential expression of Sp1 (RV> LV) may account for the interventricular gradients of KvLQT1 and HERG1 protein expression [XREF_BIBR, XREF_BIBR]."