IndraLab

Statements

PLAGL2 activates USP37. 3 / 3
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"Although PLAGL2 does not function as a deubiquitinase to impede Snail1 ubiquitination, PLAGL2 transcriptionally activates USP37, which finally interacts with and deubiquitinates Snail1 directly."
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sparser
"PLAGL2 can activate USP37, which in turn acts on Snail 1 to prevent its ubiquitination and promote gastric cancer cell proliferation and metastasis [ xref ]."
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"USP37, which is transcriptionally activated by PLAG1-like zinc finger 2, stabilizes Snail in a GSK-3β phosphorylation-dependent manner [59]."
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