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USP15 inhibits Th1 Cells. 2 / 2

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"Loss of USP15 promoted Th1 differentiation, but this phenomenon was not observed in CD8 T cells, as explained by the relatively low expression of MDM2 in CD8 T cells."

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"USP15 inhibits Th1 differentiation in vitro and in vivo in a L. monocytogenes infection model through deconjugating MDM2-mediated ubiquitination of NFATc2 [107] ."

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USP15 inhibits Th1 Cells. 2 / 2

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