IndraLab

Statements


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"Doxycycline, as a member of the tetracycline antibiotic family has effective anti-inflammatory attributes along with in-vitro inhibition of MMPs, and reduced activation of the MAPK and NFkB pathways ([MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Doxycycline can inhibit the activation of the MAPK and NFkB pathways and protects the corneal epithelial barrier function and conjunctival goblet cells [XREF_BIBR]."

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"In contrast, NFkB activity was suppressed in both HeLa TET-off and MDR-Off cell lines, suggesting that doxycycline suppresses NFkB activity."

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"In addition, the study demonstrated that doxycycline treatment causes cell cycle arrest and inhibits NFkB and STAT3 signalling, as our experiments show."