IndraLab

Statements


OTUB1 activates KRAS. 2 / 2
| 2

reach
"Whereas down-regulation or loss of function of RABEX5 in human cancers has not been reported, we found that OTUB1 expression is commonly up-regulated in a substantial subset of NSCLCs harboring wt KRAS."

reach
"Taken together, these results suggest that an increase in OTUB1 expression accelerated tumorigenic transformation of wt KRAS NSCLCs."