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Astemizole activates KCNH2-N470D. 1 / 1

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"XREF_BIBR Astemizole is able to restore not only trafficking of hERG N470D and G601S mutants, XREF_BIBR, XREF_BIBR but also trafficking inhibition induced by pentamidine in which astemizole acts as a conformation sensitive chaperone and competes with pentamidine for overlapping binding sites."

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IndraLab

Statements

Astemizole activates KCNH2-N470D. 1 / 1

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