IndraLab

Statements

GS26575 inhibits KCNH2. 3 / 3
| 3
reach
"Consequently, the IC 50 value for M1 is higher than 25 microM, indicating that M1 does not inhibit the hERG channel."
26756920
reach
"It was shown that both AVN-101 and M1 can block the hERG channel with IC 50 of 0.58 muM and 1.63 muM, respectively."
27232215
reach
"4 The results of the hERG assay show that M1 does not inhibit the hERG channel and, therefore, does not seem to present a serious risk of cardiac toxicity in humans."
26756920