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USP2 activates GATA2. 2 / 2

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"Although patient SJINF066 was an infant (9-month-old) and SJBALL021549_D1 was a 9-year-old child, the expression levels of GATA2 in these two cases were comparable, indicating that trans-activation of GATA2 by KMT2A-USP2 is not influenced by age but rather by the function of this fusion."

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"Further checking confirmed that these patients were the only two carrying this fusion in the cohort analyzed ( xref ), indicating that GATA2 could be trans-activated by KMT2A-USP2."

35087776

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IndraLab

Statements

USP2 activates GATA2. 2 / 2

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