IndraLab

Statements

IRX3 activates SCN5A. 3 / 3
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sparser
"While IRX3 alone activated the SCN5A promoter (2.3-fold change), IRX5 potentiated its effect with a 1.5-fold change."
36497174
sparser
"As previously described [ xref ], IRX3 and IRX5 physically interacted ( xref B top panel and xref ) and could cooperatively activate the SCN5A promoter ( xref B bottom panel)."
36497174
reach
"In HL-1 cells and neonatal mouse ventricular myocytes, IRX3 transfection up-regulated SCN5A and connexin-40 mRNA, which was attenuated by IRX3 mutations."
26429810