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USP13 increases the amount of WWP1. 3 / 3
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"The results revealed that USP13 knockdown significantly reduced the protein levels of WWP1, p-Akt, and p-mTOR, which was reversed by WWP1 overexpression (Fig. 5A)."
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"Conversely, we also transfected WWP1 siRNA or negative control siRNA into HCC cells overexpressing USP13 and found that WWP1 knockdown attenuated USP13-induced WWP1 expression and Akt/mTOR pathway activation (Fig.  xref B)."
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"Moreover, USP13 increased the protein level (Fig. 4B) but not the RNA level of WWP1 (Supplementary Fig. S3B and S3D)."
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