IndraLab

Statements

Clemizole inhibits KCNH2. 3 / 3
| 3
reach
"In addition, clemizole has recently been shown to block hERG channels [92]."
32033274
reach
"Our results provide the first evidence that clemizole potently blocks hERG channels, moderately inhibits cardiac I Ks, delays cardiac repolarization and thereby prolongs QT interval."
27886373
reach
"Clemizole decreased hERG current by blocking both open and closed states of the channel in a concentration dependent manner (IC 50 : 0.07 muM)."
27886373