IndraLab

Statements

CUL7 inhibits KCNH1. 4 / 4
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"14-3-3 proteins regulate cullin 7-mediated Eag1 degradation."
36717938
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"Cullin 7 mediates proteasomal and lysosomal degradations of rat Eag1 potassium channels."
28098200
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"Cul7 mediates proteasomal and lysosomal degradation of Eag1 protein, whereas over-expression of 14-3-3 notably reduces Eag1 channel activity."
36717938
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"We have previously demonstrated that the multisubunit E3 ubiquitin ligase CUL7 promotes degradation of both ER localized immature and plasma-membrane-localized mature Eag1 proteins."
33647316