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2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) inhibits IRF3. 1 / 1

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"Luteolin suppressed activation of Interferon regulatory factor 3 (IRF3) and NFkappaB induced by TLR3 and TLR4 agonists resulting in the decreased expression of target genes such as TNF-alpha, IL-6, IL-12, IP-10, IFNbeta, CXCL9, and IL-27 in macrophages."

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IndraLab

Statements

2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) inhibits IRF3. 1 / 1

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