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ATP activates VCPIP1. 1 / 1

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"34 Considering the key role in contact with VCP by VCPIP1 Y623 and F638, which are the neighboring residues of K632 and K646, UFD1 ubiquitination might have a direct effect on their interaction and thus regulate Golgi membrane dynamics.In conclusion, our findings uncover the high‐resolution structure of the P97/VCP‐VCPIP1 complex and reveal the unique and unexpected binding modes between the ATP‐driven substrate unfoldase P97/VCP and the deubiquitinase VCPIP1."

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IndraLab

Statements

ATP activates VCPIP1. 1 / 1

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