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JNK activates USP49. 1 / 1
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"Moreover, it has been reported that USP49 overexpression could inhibit JNK1/2 activation and reduce human cardiomyocyte apoptosis, while JNK1/2 inhibitor treatment (SP600125) suppressed USP49 knockdown-induced JNK1/2 activation and cardiomyocyte apoptosis [ xref ]."