IndraLab

Statements

Sirolimus increases the amount of UCHL1. 2 / 2
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reach
"Though UCHL1 transcription was maintained after SE, we observed downregulation of the pro translational antisense Uchl1 (AsUchl1) and confirmed that both AsUchl1 and rapamycin can increase UCHL1 expression in vivo."
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reach
"Furthermore, as AsUchl1 export into the cytoplasm increases following mTOR inhibition [XREF_BIBR], we confirmed that rapamycin, a potent mTOR inhibitor and anti-epileptogenic agent [XREF_BIBR, XREF_BIBR], increased UCHL1 expression."
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