Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Sirolimus increases the amount of UCHL1. 2 / 2

| 2

➶

reach

"Though UCHL1 transcription was maintained after SE, we observed downregulation of the pro translational antisense Uchl1 (AsUchl1) and confirmed that both AsUchl1 and rapamycin can increase UCHL1 expression in vivo."

28397067

➶

reach

"Furthermore, as AsUchl1 export into the cytoplasm increases following mTOR inhibition [XREF_BIBR], we confirmed that rapamycin, a potent mTOR inhibitor and anti-epileptogenic agent [XREF_BIBR, XREF_BIBR], increased UCHL1 expression."

28397067

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...