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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TP53 activates ubiquitinated TP53. 2 / 2

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"As expected, co-expression of MDM2 and p53 produced a ladder of ubiquitinated p53 (Ub-p53) products upon MG132 treatment."

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"Wt-ING1 stabilized both ubiquitinated and non ubiquitinated forms of p53 (XREF_FIG, lane 2), while MDM2 only increased levels of p53 monoubiquitinated on several residues (XREF_FIG, top panel, lane 5), but failed to promote accumulation of non ubiquitinated p53 (XREF_FIG, third panel, lane 5)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...