IndraLab

Statements

USP25 activates Hedgehog. 2 / 2
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"Another mechanism by which USP21 modulates Hh signaling focuses on its regulation of Gli1."
35846989
reach
"Our results suggest that endogenous USP21 positively regulates Hh signaling through two independent mechanisms : firstly, we have previously shown that USP21 depletion interferes with the formation of primary cilia, the specialised organelles that host the initiation of the Hh signaling cascade in untransformed mammalian cells."
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