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ATXN3 inhibits BRCA1. 1 / 1
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"Consistent with defective DSB induced ubiquitylation, we found that depletion of ataxin-3 also significantly reduced both BRCA1 (Fig XREF_FIG D) and 53BP1 accumulation (Fig XREF_FIG E) to laser inflicted DNA damage, as well as to ionizing radiation induced foci (XREF_SUPPLEMENTARY and XREF_SUPPLEMENTARY)."