IndraLab

Statements

Lomefloxacin inhibits KCNH2. 2 / 2
| 2
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"For example, at the same concentrations, norfloxacin and lomefloxacin inhibited hERG currents by 2.8% +/- 3.6% and 12.3% +/- 4.7%, respectively."
| PMC
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"Sparfloxacin blocked HERG currents half-maximally (IC (50) value) at a concentration of 33.2 microM, whereas norfloxacin and lomefloxacin each tested at a concentration of 300 microM inhibited HERG currents only by 2.8 +/-3.6% and 12.3 +/-4.7%, respectively."
17027138