IndraLab

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"The interaction between OTUD1 and PRDX1 prompts us to examine the regulatory functions of OTUD1 on PRDX1, including the stability and ubiquitination status."

No evidence text available

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"Subsequent Co-IP experiments confirmed the direct interaction between OTUD1 and PRDX1 in both Human Embryonic Kidney 293T (HEK-293T) cells and BMDMs (Figure xref D-E)."

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"These data indicated that PRDX1 rescued osteoclastogenesis and mitochondrial dysfunction enhanced by OTUD1 deficiency, highlighting the critical regulatory role of the OTUD1-PRDX1 axis in osteoclastogenesis."