IndraLab

"Although most of this subset remains genotype negative, mutations occurring at 1% frequency have been identified in a variety of ion channels or channel interacting proteins: cytoskeletal protein ankyrin B (LQT4), xref KCNQ1 beta-subunit minK (LQT5), xref HERG beta-subunit MiRP1(LQT6), xref potassium channel Kir2.1 (LQT7), xref L-type calcium channel (Timothy syndrome/LQT8), xref caveolin-3 (LQT9), xref beta4 subunit of the sodium channel (LQT10), xref AKAP9 -encoded adaptor protein yotiao, which interacts with KCNQ1 (LQT11), xref and cytoskeletal sodium channel regulator α 1 -syntrophin (LQT12). xref "