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Statements

USP42 inhibits Wnt. 4 / 4
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reach
"USP42 protects ZNRF3 and RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling."
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"Accordingly , USP42 increases the turnover of LRP6 and Frizzled ( FZD ) receptors and inhibits Wnt signalling ."
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reach
"Accordingly, USP42 increases the turnover of LRP6 and Frizzled (FZD) receptors and inhibits Wnt signalling."
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eidos
"We conclude that USP42 inhibits Wnt signalling in HCT116 cells by destabilising the Wnt receptors , independently of its roles in p53 response to genotoxic stress ."
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