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USP4 leads to the deubiquitination of RHEB. 2 / 2

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"Thus, we propose a mechanistic model whereby Rheb mediated mTORC1 activation is dictated by a dynamic opposing act between Rheb ubiquitination and deubiquitination that are catalyzed by RNF152 and USP4 respectively."

30514904

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ubibrowser

"EGF enhances the deubiquitination of Rheb through AKT-dependent USP4 phosphorylation, leading to the release of Rheb from the TSC complex"

30514904

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IndraLab

Statements

USP4 leads to the deubiquitination of RHEB. 2 / 2

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