IndraLab

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UCHL3 increases the amount of ABCG2. 2 / 2
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"FACS analysis showed that inhibition of UCHL3 using TCID reduced CD338 expression and the percentage of SP cells among A549 cells overexpressing UCHL3 (Fig. 7e, f)."
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"As expected, overexpression of UCHL3 increased the expression of ABCG2, c-Myc and KLF4, genes associated with stemness, at the protein level in A549 and H1299 cells (Fig. 5b, c), while depletion of UCHL3 decreased their protein expression (Fig. 5d)."
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