IndraLab

Statements

OTUB1 inhibits JAK. 3 / 3
| 3
reach
"We hypothesized that OTUB1 potentially inhibits the JAK/STAT1 pathway activity promoting the development of GBM."
39006090
reach
"Mechanistically, OTUB1 inhibited IFN-gamma-induced Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling by K48 deubiquitination and stabilization of the JAK2 inhibitor suppressor of cytokine signaling 1 (SOCS1)."
30944096
reach
"We further found that OTUB1 inhibited the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway to regulate the growth of GBM."
39006090