IndraLab

Statements

BRCC3 activates TRAF2. 5 / 5
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"BRCC3 binds to and synergizes with TRAF2 to activate NF-kappaB signaling."
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"Our results indicate that high BRCC3 expression activates NF-kappaB signaling by targeting TRAF2 for activation, which in turn facilitates tumorigenesis in bladder cancer."
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"We found that BRCC3 increased the activation NF-κB signaling pathway together with the upstream molecules TNFR and TRAF2 (Figure 5A)."
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"BRCC3 Promotes Tumorigenesis of Bladder Cancer by Activating the NF-kappaB Signaling Pathway Through Targeting TRAF2."
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"Here, we found that high expression of BRCC3 promoted tumorigenesis through targeting the TRAF2 protein."
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