IndraLab

Statements

THBS1 binds LRP1 and CALR. 4 / 4
| 1 3
sparser
"The N-terminal domain of TSP1 binds to the calreticulin-LRP1 receptor co-complex to signal down-regulation of cell adhesion and increased cell motility through focal adhesion disassembly."
18653767
sparser
"For example, a pro-migratory signal is generated when LRP1 binds and internalizes the complex of cell surface calreticulin and thrombospondin-1 in coronary artery endothelial cells ( xref , xref )."
19549899
sparser
"Thrombospondin 1 binding to calreticulin-LRP1 signals resistance to anoikis."
29380675
reach
"Despite the focus on TSP-1 as a regulator of TGF-β activation in glaucoma, in contrast, the possible functions of the TSP-1/Calr/LRP1 complex in glaucoma remain unexplored and unknown."
35693935