IndraLab

Statements

MAP3K7 binds USP29. 14 / 14
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37304282
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"Moreover, glutathione s-transferase (GST) precipitation assay further demonstrated a direct interaction between USP29 and TAK1 (Figure 7B)."
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reach
"Further results demonstrated that USP29 directly bound and interacted with TAK1."
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No evidence text available
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sparser
"Specifically, in the context of cardiac hypertrophy, USP29 directly interacts with TAK1 through its binding region (aa 284 to 922), deubiquitinating TAK1 in its K63‐linked polyubiquitination chain within the region (aa 1 to 306) of TAK1 itself."
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sparser
"USP29 directly interacted with TAK1, inhibiting its ubiquitination and phosphorylation."
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"ELAVL1 silencing inhibits M1 microglial polarization via the USP29-TAK1 axis, promotes neuronal differentiation of NSCs, and facilitates SCI repair."
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"To further validate the regulatory effect of ELAVL1 on the USP29-TAK1 axis, HMC3 cells were co-infected with shELAVL1 and shUSP29 lentiviruses, followed by LPS-induced polarization (Fig. xref )."
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