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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP5 activates Carcinogenesis. 3 / 3

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"USP5 promotes tumorigenesis in HCC through the inactivation of p14 -p53 signaling."

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"USP5 expression promotes tumorigenesis in many cancers , like in non-small cell lung cancer overexpression of USP5 stabilizes the beta-catenin protein [ 13 ] ."

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"It has been reported that USP5 promotes tumor proliferation and tumorigenesis through the deubiquitination of histone deacetylase 2 ( HDAC2 ) ( Du et al ., 2019 ) and beta-catenin ( Ma et al ., 2018 ) ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...