IndraLab

Statements

COPS5 inhibits ERN1. 2 / 4

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"It is unknown how the association between JAB1 and IRE1alpha is regulated or whether JAB1 prevents the kinase activity of IRE1alpha."

28550308

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"Upon ER stress, JAB1 dissociates from IRE1alpha, allowing IRE1alpha to splice XBP1 mRNA into XBP1s, suggesting that JAB1 inhibits IRE1alpha through its binding 55."

28550308

INDRA sources:

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IndraLab

Statements

COPS5 inhibits ERN1. 2 / 4

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