IndraLab

Statements

CACNA1D activates Neoplasm Invasiveness. 2 / 2
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"In particular, CACNA1D, which localizes to filopodia tips and contributes to cancer cell invasion in vitro (shown in this study), was found to be expressed in patient samples in all major breast cancer subtypes."
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"Importantly, individual silencing of CACNA1D or CACNA1S gene expression using multiple siRNA oligos (XREF_SUPPLEMENTARY) decreased both filopodia formation and cancer cell invasion (XREF_FIG), indicating that CACNA1D and CACNA1S are likely to synergistically support filopodia formation and cancer cell invasion in MDA-MB-231 cells."
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