IndraLab

Statements

Prostaglandin E2 inhibits IFNB1. 6 / 6
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"PGE 2 suppresses IFN-beta induction and boosts IL-10 release by costimulated macrophages."
34129840
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"Treating mice with prostaglandin E2 and zileuton, which limit IFNbeta induction, confers tolerance to Mtb [XREF_BIBR] and zileuton has been developed as a drug that can be administered to TB patients to enhance the efficacy of antibiotic treatment [XREF_BIBR]."
27500737
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"We found that PGE2 could inhibit the differentiation of MDSCs and PMN-MDSCs (Fig.  xref c) and IFN-β could inhibit the differentiation of M-MDSCs significantly (Fig.  xref d)."
32727564
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"Although we observed PGE2 inhibition of endogenous IFNbeta, it was only partial (approx."
28062696
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"PGE2 suppresses IFNbeta production in macrophages."
28062696
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"In turn, active PGE2 can block the IFN-β (interferon β), which downregulates MMP-9 production and upregulates tissue inhibitors of matrix metalloproteinases I (TIMP) (MMP-9 inhibitor)."
38003287