IndraLab

Statements

PLD inhibits KCNH2. 3 / 3
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"77.0% of PLD positive compounds also blocked hERG channel; 3."
23856051
reach
"This method was used effectively to identify and distinguish the toxicophores of drug candidates that block the human Ether-a-go-go related gene (hERG) potassium channel or that induce phospholipidosi[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
37586644
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"The results indicated that a positively charged hERG blocker has a greater chance to induce PLD than a neutral compound, and a neutral or negatively charged PLD inducer is less likely to inhibit hERG function."
23856051