IndraLab

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BAP1 inhibits H2AK119ub. 2 / 2

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"Yet, on the other hand, the loss of BAP1 in mouse ESCs leads to spreading and genome-wide accumulation of H2AK119ub, resulting in reductions in global gene expression [95,96]."

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"The authors suggest that the function of BAP1 is to limit the spread of H2AK119ub to relevant target sites."

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INDRA sources:

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IndraLab

Statements

BAP1 inhibits H2AK119ub. 2 / 2

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