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JOSD2 inhibits Hypertrophy. 2 / 2

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"Josd2 gene knockout aggravated cardiac dysfunction and hypertrophy in mice, whereas cardiac overexpression of JOSD2 mediated by the AAV9 vector prevented angiotensin II-induced cardiac hypertrophy."

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"Deubiquitinase JOSD2 improves calcium handling and attenuates cardiac hypertrophy and dysfunction by stabilizing SERCA2a in cardiomyocytes."

39195964

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Statements

JOSD2 inhibits Hypertrophy. 2 / 2

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