IndraLab

Statements

USP38 activates Mice. 4 / 4
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"USP38 deficiency improves cardiac function and reduces the susceptibility of VAs in mice with HF induced by pressure overload.."
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"Conversely, cardiac-specific overexpression of USP38 exacerbated cardiac diastolic dysfunction and increased susceptibility to VAs in HFpEF mice."
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"It was found that overexpression of USP38 increased vulnerability to AF in diabetic mice."
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"Together, these results demonstrate that USP38 promotes the activation of the TBK1/AKT/CaMKII signaling pathway in mice with HF."
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