IndraLab

Statements

USP33 deubiquitinates ROBO1. 8 / 9
1 | 8
reach
"Moreover, USP33 could deubiquitinate and stabilize Robo1 and was responsible for the redistribution of Robo1 to the plasma membrane [42]."
36582601
reach
"USP33 deubiquitinates and stabilizes Robo1."
25242263
reach
"These results show that USP33 mediates Slit-Robo signaling by deubiquitinating and stabilizing Robo1 in CRC cells (XREF_SUPPLEMENTARY)."
25242263
reach
"USP33 mediates Slit2 signaling by deubiquitinating and stabilizing Robo1."
25242263
reach
"Cell based assays support a model in which USP33 reverses Robo1 ubiquitination : knockdown of USP33 increases levels of ubiquitinated Robo1, while USP33 overexpression reduces ubiquitinated Robo1 levels [XREF_BIBR]."
21704388
reach
"Though direct deubiquitination of Robo1 by USP33 has not been reported, it is reasonable to speculate that USP33 deubiquitinates and thus rescues Robo1 from degradation during the Slit response."
21704388
reach
"In addition, Xia et al. demonstrated that USP33 deubiquitinates and stabilizes ROBO1, which is required for the SLIT2-mediated inhibition of EMT and GC cell metastasis [57]."
36497313
reach
"USP33 deubiquitinates ROBO1 in lung cancer cells to maintain its stability, thereby regulating SLIT2 activity and inhibiting cancer cell metastasis [XREF_BIBR]."
29743814